Just want to share my experiences in case they might be helpful to someone else.
I had awful depression when I took Reglan during my second trimester. I attempted to take Zoloft, but found out that w/ Reglan, the antidepressant doesn't have time to absorb b/c the Reglan pushes everything through the system so quickly (This per the psychiatrist I ended up seeing). So it appeared that the Zoloft wasn't working, when in fact the problem was the Reglan.
I felt like I was going through withdrawl tapering off the Reglan - and stopping Reglan suddenly can be dangerous.
I ended up taking Axiphex, which worked well for the remainder of my pregnancy and didn't interfere w/ the antidepressants. Also, no problems when I stopped taking the Aciphex suddenly when my little one was born.
It was bad enough having to explain HG and defend myself regarding all of those symptoms. Having to deal with and explain the depressive symptoms was just icing on the cake. And I'm a social worker who is familiar w/ and able to articulate depressive symptoms. I was always so self conscious, as if I came across as a hystroinic, hypochondriac.
I wish I could have captured the look on my son's pediatrician's face when I listed all the meds I had taken during my pregnancy. The guilt is and was terrible. Even now, this bothers me, as I'm planning for my second pregnancy and reliving all of this.